Article Text

Download PDFPDF
Prescribing for pregnancy: managing prescribing for women with mental health diagnoses
  1. Louise Page
  1. Obstetrics and Gynaecology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
  1. Correspondence to Louise Page, Obstetrics & Gynaecology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK; Louise.Page{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Key learning points

  • Mental illness during pregnancy or in the first year after birth is common

  • Preconception care is important to optimise and stabilise medication and the mental health condition prior to conception

  • Aim to prescribe the lowest effective dose, with monotherapy where possible

  • Advise women not to stop medication without discussion with a practitioner experienced in caring for women with mentalillness in pregnancy

  • A multi-professional approach, with the woman and her family at the centre is key

  • There are many safe options for pharmacological treatment for women with mental illness in the perinatal period

Introduction and general principles

Up to 20% of women will experience a mental health problem during pregnancy or in the first year after birth.1 The impact can be widespread affecting not only the woman but also her partner and their children. The economic impact of mental illness for a 1-year cohort of births in the UK is over £8 billion.2 Women may enter pregnancy with an existing mental health diagnosis, for others illness can develop for the first time during pregnancy or in the postpartum period. Many women will benefit from psychological interventions and certainly for women with mild to moderate illness this should be the first-line therapeutic intervention.3 Some women will be taking psychotropic medication prior to pregnancy and ideally, they would have received preconception care in order to optimise and stabilise their medication and their condition prior to conception. The preconception consultation should also take the opportunity to share general advice for women such as optimising their body mass index (BMI), stopping smoking and starting folic acid supplementation. For more details on general prepregnancy care, please refer to the first article in this series (Girling J. Prescribing for pregnancy: general prepregnancy care. DTB 2019;57:168–72).4

When a pharmacological intervention is required in pregnancy, the aim should always be …

View Full Text


  • Competing interests None declared. Disclosure of conflicts of interest form(s) are published online as supplementary files.

  • Provenance and peer review Commissioned; externally peer reviewed.