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Iprindole a new tricyclic antidepressive

Abstract

There are two main kinds of antidepressive* compounds - monoamineoxidase (MAO) inhibitors and iminodibenzyl (tricyclic) derivatives. At present the number of the latter is still increasing, though there has been no new MAO inhibitor for five years. There are now eight different ‘tricyclic’ compounds available as thirteen different products; is there a need for yet another?

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Footnotes

  • * ‘Antidepressive’ is now preferred to ‘antidepressant’ because these drugs do not antagonise depressants (i.e. drugs depressing the nervous system), but are active in depressive illness.