Article Text
DTB drug review
Naldemedine for opioid-induced constipation
Abstract
Generic name: Naldemedine tosylate
Brand name: Rizmoic
Formulation: 200 mcg film-coated tablets
Market Authorisation holder: Shionogi B.V
Indication: Treatment of opioid-induced constipation in adult patients who have previously been treated with a laxative
Dose: 200 mcg/day, taken at the same time every day. Naldemedine may be used with or without a laxative. It must be discontinued if treatment with the opioid is discontinued.
Cost: £41.72 for 28 tablets
Classification: Prescription only medicine subject to additional monitoring (▼)
- constipation
- chronic pain