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What does the TIME study tell us about morning and evening dosing of antihypertensive medication?
  1. Teck K Khong12,
  2. George S Lin3
  1. 1 Clinical Pharmacology, St George's University of London, London, UK
  2. 2 Blood Pressure Unit, St George's Hospital, London, UK
  3. 3 St George's University of London, London, UK
  1. Correspondence to Dr Teck K Khong, Clinical Pharmacology, St George's University of London, London SW17 0RE, UK; tkhong{at}sgul.ac.uk

Abstract

Commentary on: Mackenzie IS, Rogers A, Poulter NR, et al. Cardiovascular outcomes in adults with hypertension with evening vs morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial. Lancet. 2022;400:1417–25.

  • Drug-Related Side Effects and Adverse Reactions
  • Health Care Quality, Access, and Evaluation

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Footnotes

  • Series co-ordinator Dr Teck Khong, DTB Associate Editor, Clinical Pharmacology, St George’s, University of London, UK

  • Competing interests None declared. Refer to the online supplementary files to view the ICMJE form(s).

  • Provenance and peer review Commissioned; internally peer reviewed.

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