Septrin (BW) and Bactrim (Roche) are two different forms of a combination of trimethoprim and sulphamethoxazole effective against a wide range of bacteria. Although sulphonamides alone are often active against common pathogens, their usefulness has waned because many organisms have become resistant, and more effective drugs have been introduced. The antibacterial value of the sulphonamides has been increased and the range of susceptible organisms extended by the combination with trimethoprim.
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