Article Text

Download PDFPDF
Oxypertine (integrin) - now promoted’ for the treatment of anxiety


We reviewed oxypertine (Integrin) in 1967, soon after it was introduced as a major tranquilliser.1 Structurally it is related to 5-hydroxytryptamine. Capsules containing a lower dose than the original tablets are now being marketed with claims that it is a ‘fundamental’ treatment for anxiety and that ‘it goes straight to the root of the problem and combats the disturbed brain-chemistry that underlies anxiety’. Like some other major tranquillisers, e.g. reserpine, oxypertine does lower amine levels in the central nervous system in animal preparations.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.