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Review of: Stockings E, et al. Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies. Pain 2018;159:1932–54.
Key learning points
There has been increasing interest in the use of cannabis and cannabinoids for the treatment of chronic pain.
This review analysed outcomes based on cannabinoid type and specific chronic non-cancer pain conditions.
Compared with placebo, the clinical impact of cannabinoids on chronic pain was slight and adverse effects were common.
The authors of a systematic review and meta-analysis concluded that cannabinoids are unlikely to be highly effective medicines for chronic non-cancer pain.1
This systematic review and meta-analysis included 104 studies (47 randomised controlled trials [RCTs]), involving a total of 9958 participants (median age 42 years), that compared cannabinoids with placebo or active comparator for the treatment of chronic non-cancer-related pain (CNCP).1 The studies included neuropathic pain, fibromyalgia, rheumatoid arthritis and …
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