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MHRA issues further update on fluoroquinolone safety

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Key learning points

  • The Medicines and Healthcare products Regulatory Agency (MHRA) has issued another safety update on fluoroquinolone antibiotics.

  • Fluoroquinolones must now only be used when other antibiotics are inappropriate.

  • Patients should be advised to stop taking a fluoroquinolone antibiotic at the first sign of a serious adverse reaction.

The licensed indications for all systemic fluoroquinolones have been updated to restrict their use to situations in which other commonly recommended antibiotics are inappropriate.1


In August and September 2023, the Medicines and Healthcare products Regulatory Agency (MHRA) issued two safety updates on the use of fluoroquinolone antibiotics.1–3 The first update reminded healthcare professionals that systemic fluoroquinolone antibiotics are associated with a risk of …

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  • Provenance and peer review Commissioned; internally peer reviewed.