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Repository antigens for hay fever


Desensitization for hay fever and other allergies normally requires repeated injections of aqueous extracts of the allergen, at cautiously progressive doses. Twenty years ago, it was shown that a water-in-oil emulsion of antigens had a prolonged immunological effect in animals; a few years later M. H. Loveless (Amer. J. med. Sci. 1947, 214, 559) used a similar water-in-oil emulsion clinically, and many allergists have since experimented with “single visit” repository preparations.

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