PT - JOURNAL ARTICLE ED - BMJ Publishing Group Ltd TI - Oxpentifylline (trental) in peripheral arterial disease AID - 10.1136/dtb.14.15.59 DP - 1976 Jul 16 TA - Drug and Therapeutics Bulletin PG - 59--60 VI - 14 IP - 15 4099 - http://dtb.bmj.com/content/14/15/59.short 4100 - http://dtb.bmj.com/content/14/15/59.full SO - Drug Ther Bull1976 Jul 16; 14 AB - Vasodilators are disappointing in the treatment of peripheral vascular disease. There is little evidence that they either increase blood flow or improve symptoms.1 Oxpentifylline (Trental - Hoechst) is a dimethyl xanthine related to caffeine, theobromine and theophylline. It is a weak vasodilator, but the maker claims that it also reduces blood viscosity which is increased in patients with peripheral vascular disease.2 3