RT Journal Article SR Electronic T1 Oxpentifylline (trental) in peripheral arterial disease JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 59 OP 60 DO 10.1136/dtb.14.15.59 VO 14 IS 15 YR 1976 UL http://dtb.bmj.com/content/14/15/59.abstract AB Vasodilators are disappointing in the treatment of peripheral vascular disease. There is little evidence that they either increase blood flow or improve symptoms.1 Oxpentifylline (Trental - Hoechst) is a dimethyl xanthine related to caffeine, theobromine and theophylline. It is a weak vasodilator, but the maker claims that it also reduces blood viscosity which is increased in patients with peripheral vascular disease.2 3