PT  - JOURNAL ARTICLE
ED - BMJ Publishing Group Ltd
TI  - Low-dose heparin preparations for prophylactic use
AID  - 10.1136/dtb.15.6.21
DP  - 1977 Mar 18
TA  - Drug and Therapeutics Bulletin
PG  - 21--22
VI  - 15
IP  - 6
4099  - http://dtb.bmj.com/content/15/6/21.short
4100  - http://dtb.bmj.com/content/15/6/21.full
SO  - Drug Ther Bull1977 Mar 18; 15
AB  - Administration of low doses of heparin before and after surgery can reduce the incidence of venous thrombosis and pulmonary embolism during, and after, major operations.1 2 It is acceptably safe, except in patients with bleeding disorders. Traditional multi-dose ampoules of heparin are both inconvenient for this purpose and wasteful, and this may have hindered the widespread adoption of low-dose heparin prophylaxis. Other prophylactic measures include infusion of dextran-70,3 and rhythmical4 or graded static5 compression of the calves.