RT Journal Article
SR Electronic
T1 Praxilene (naftidrofuryl)
JF Drug and Therapeutics Bulletin
JO Drug Ther Bull
FD BMJ Publishing Group Ltd
SP 93
OP 94
DO 10.1136/dtb.10.24.93
VO 10
IS 24
YR 1972
UL http://dtb.bmj.com/content/10/24/93.abstract
AB Naftidrofuryl (Praxilene - Lipha) is the acid oxalate of (β-naphthyl-l-β1 tetrahydrofuryl diethanolamine isobutyrate and is therefore unrelated to nicotinic acid or xanthine. In animals it shows peripheral and cerebral vasodilator properties and is claimed to act directly on brain cells increasing cerebral metabolism.1 It also induces resistance to hypoxic damage as shown by EEG recordings. It is now being marketed for use in man as a ‘cerebral activator’.