RT Journal Article SR Electronic T1 Appetite suppressants reassessed JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 35 OP 36 DO 10.1136/dtb.20.9.35 VO 20 IS 9 YR 1982 UL http://dtb.bmj.com/content/20/9/35.abstract AB Since we last discussed appetite suppressants1 their limitations have become better understood, and this prompts a reassessment of their place in the management of obesity. Centrally acting appetite suppressant drugs or anorectics reduce physiological hunger by an action on the brain, presumably interfering with the pathways concerned in the regulation of food intake.2 Methylcellulose (Cellucon, Celevac, Cologel) and sterculia (Prefil) act by filling the stomach and are less effective clinically but are safe.3 This article discusses only those drugs with central actions.