RT Journal Article
SR Electronic
T1 Surgery in parkinsonism
JF Drug and Therapeutics Bulletin
JO Drug Ther Bull
FD BMJ Publishing Group Ltd
SP 65
OP 66
DO 10.1136/dtb.1.17.65
VO 1
IS 17
YR 1963
UL http://dtb.bmj.com/content/1/17/65.abstract
AB For reasons that are still unknown a destructive lesion in one cerebral hemisphere, correctly placed and of appropriate size, can relieve the tremor and rigidity in the opposite limbs. The relief is known to last for at least five years in favourable cases. Symptoms in the arms are more successfully treated than in the legs and complete and permanent relief of rigidity is more easily achieved than of tremor. Rigidity of the face, tremor of the tongue, rigidity of the trunk, slowness and other disorders of gait, and weakness, slurring and monotony of speech are among the symptoms which respond least. Drug treatment is usually continued post-operatively but often in smaller doses, and post-operative physiotherapy may help considerably.