PT  - JOURNAL ARTICLE
ED  - ,
TI  - Penicillamine in rheumatoid arthritis
AID  - 10.1136/dtb.11.8.31
DP  - 1973 Apr 13
TA  - Drug and Therapeutics Bulletin
PG  - 31--32
VI  - 11
IP  - 8
4099  - http://dtb.bmj.com/content/11/8/31.short
4100  - http://dtb.bmj.com/content/11/8/31.full
SO  - Drug Ther Bull1973 Apr 13; 11
AB  - The use of penicillamine (Distamine - Dista; Cuprimine - MSD) for rheumatoid arthritis followed the observation that its administration caused a fall in levels of rheumatoid factor in the serum.1 2 This fall was associated with clinical improvement, and both continued for some months after the drug was stopped.3–5 The authors suggested that the serological changes were not due solely to intravascular depolymerisation of rheumatoid factor, but to some effect on the disease process.