RT Journal Article SR Electronic T1 Topical corticosteroids in ulcerative colitis JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 5 OP 7 DO 10.1136/dtb.13.2.5 VO 13 IS 2 YR 1975 UL http://dtb.bmj.com/content/13/2/5.abstract AB Since the usefulness of topical corticosteroids in the treatment of ulcerative colitis was first reported1 double-blind trials have confirmed their effectiveness, and they are now widely used.2 For disease localised to the rectum suppositories, and for more extensive disease, retention enemas containing various corticosteroids are available (see table). In severe cases these preparations also valuably supplement systemic corticosteroid therapy, with or without sulphasalazine (Salazopyrin).