RT Journal Article
SR Electronic
T1 Ranitidine v. cimetidine in peptic ulcer
JF Drug and Therapeutics Bulletin
JO Drug Ther Bull
FD BMJ Publishing Group Ltd
SP 57
OP 59
DO 10.1136/dtb.20.15.57
VO 20
IS 15
YR 1982
UL http://dtb.bmj.com/content/20/15/57.abstract
AB For five years cimetidine (Tagamet - SKF) has been the only histamine H2-receptor antagonist available for the treatment of peptic ulceration.1 It has now been joined by ranitidine (Zantac - Glaxo), an H2-receptor antagonist which like cimetidine decreases gastric acid secretion both basal and in response to all stimuli.2, 3 Neither drug affects the H1 receptors in bronchial, vascular or intestinal smooth muscle. Is there anything to choose between them?