TY - JOUR T1 - Hydromet: methyldopa + hydrochlorothiazide JF - Drug and Therapeutics Bulletin JO - Drug Ther Bull SP - 55 LP - 56 DO - 10.1136/dtb.2.14.55 VL - 2 IS - 14 A2 - , Y1 - 1964/07/10 UR - http://dtb.bmj.com/content/2/14/55.abstract N2 - Hydromet (MSD) is a mixture of 250 mg methyldopa with 15 mg hydrochlorothiazide in a tablet offered for the treatment of hypertension. Both drugs may lower the blood pressure when it is raised. In a double-blind trial1 a combination of the two (given in separate tablets) was found to be better than either drug alone combined with a placebo. The dose of hydrochlorothiazide was 100 mg daily and the dose of methyldopa was increased from 1 to 2 G daily after the first week. ER -