TY - JOUR T1 - Three new non-sedative antihistamines: worth keeping an eye open for JF - Drug and Therapeutics Bulletin JO - Drug Ther Bull SP - 38 LP - 40 DO - 10.1136/dtb.28.10.38 VL - 28 IS - 10 A2 - , Y1 - 1990/05/14 UR - http://dtb.bmj.com/content/28/10/38.abstract N2 - Oral antihistamines are used to relieve symptoms in allergic rhinitis, conjunctivitis, urticaria and eczema. Traditional H1 receptor antagonists have sedative, and in some cases anticholinergic, side effects. A significant advance has been the development of more specific H1 antagonists in which these other properties are greatly reduced. Terfenadine and astemizole were the first;1 acrivastine (Semprex - Wellcome), cetirizine (Zirtek - A&H) and loratadine (Clarityn - Schering Plough) are three newer ones. Are they better than terfenadine and astemizole? ER -