RT Journal Article SR Electronic T1 ▾ Ondansetron to prevent chemotherapy-induced vomiting JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 21 OP 23 DO 10.1136/dtb.30.6.21 VO 30 IS 6 YR 1992 UL http://dtb.bmj.com/content/30/6/21.abstract AB Nausea and vomiting are very common within a few hours of administration of cytotoxic drugs, and may be severe enough to interrupt treatment or interfere with nutrition. The resulting dehydration may exacerbate toxic effects of the drugs. Ondansetron (Zofran – Glaxo) is an important new type of drug for the prevention of vomiting and nausea induced by chemotherapy and radiotherapy.