RT Journal Article
SR Electronic
T1 ▾ Securon SR: sustained-release verapamil
JF Drug and Therapeutics Bulletin
JO Drug Ther Bull
FD BMJ Publishing Group Ltd
SP 47
OP 48
DO 10.1136/dtb.25.12.47
VO 25
IS 12
YR 1987
UL http://dtb.bmj.com/content/25/12/47.abstract
AB Verapamil was the first calcium antagonist in clinical use and its value in the treatment of angina, hypertension and cardiac arrhythmias is well established.1 Standard verapamil tablets have to be taken twice or three times daily but now a scored sustained-release (s/r) tablet containing 240mg verapamil (Securon SR - Knoll) has been licensed for the treatment of mild to moderate hypertension. A single dose is claimed to lower blood pressure for 24 hours. As we have noted before,2 the pros and cons of s/r products need careful assessment.