RT Journal Article SR Electronic T1 Dianette for women with acne JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 15 OP 16 DO 10.1136/dtb.28.4.15 VO 28 IS 4 YR 1990 UL http://dtb.bmj.com/content/28/4/15.abstract AB Diane, a combination of ethinyloestradiol 50μg + cyproterone acetate 2mg, was introduced in 1983 for the treatment of acne in women who had not responded to topical preparations and/or oral antibiotics,1 and for mild to moderate idiopathic hirsutism.2 In keeping with recent attempts to reduce the oestrogen content of all oestrogen/progestagen combinations, Diane has been withdrawn and replaced by Dianette which contains ethinyloestradiol 35µg + cyproterone 2mg. Is it as effective?