RT Journal Article
SR Electronic
T1 Cimetidine and non-ulcer dyspepsia
JF Drug and Therapeutics Bulletin
JO Drug Ther Bull
FD BMJ Publishing Group Ltd
SP 3
OP 4
DO 10.1136/dtb.24.1.3
VO 24
IS 1
YR 1986
UL http://dtb.bmj.com/content/24/1/3.abstract
AB Many patients with dyspepsia do not appear to have organic disease.1 Cimetidine (Tagamet) is of proven efficacy in the treatment of peptic ulcer and reflux oesophagitis, but is widely used for the treatment of dyspepsia without investigation.2, 3 The data sheet for cimetidine now states that the drug is indicated “where reduction of gastric acid by Tagamet has been shown to be beneficial: persistent dyspeptic symptoms with or without ulceration, particularly meal-related upper abdominal pain”. Is this indication valid?