PT  - JOURNAL ARTICLE
ED  - ,
TI  - Novo human insulin - the same but different
AID  - 10.1136/dtb.28.6.24
DP  - 1990 Mar 19
TA  - Drug and Therapeutics Bulletin
PG  - 24--24
VI  - 28
IP  - 6
4099  - http://dtb.bmj.com/content/28/6/24.short
4100  - http://dtb.bmj.com/content/28/6/24.full
SO  - Drug Ther Bull1990 Mar 19; 28
AB  - Unannounced to prescribers or patients, Novo Nordisk have changed the manufacturing process of their human insulins from enzymatic modification of pig insulin (emp) to direct biosynthesis of genetically engineered yeast cells (pyr). The preservative for Human Actrapid insulin has also been changed from phenol to meta-cresol. No warning of this change was sent to pharmacists, doctors, diabetes specialists or patients.