PT - JOURNAL ARTICLE ED - , TI - An oestrogen patch for hormone replacement therapy AID - 10.1136/dtb.27.24.93 DP - 1989 Nov 27 TA - Drug and Therapeutics Bulletin PG - 93--95 VI - 27 IP - 24 4099 - http://dtb.bmj.com/content/27/24/93.short 4100 - http://dtb.bmj.com/content/27/24/93.full SO - Drug Ther Bull1989 Nov 27; 27 AB - Oestrogen for hormone replacement therapy (HRT) is now well established for treating perimenopausal symptoms and preventing osteoporosis.1 It also protects against ischaemic heart disease and stroke.2,3 A transdermal delivery method for oestradiol (Estraderm TTS – transdermal therapeutic system) as a ‘patch’ now exists. What advantage does the patch offer over oral or implanted oestrogen?