TY - JOUR T1 - Management of bronchiectasis JF - Drug and Therapeutics Bulletin JO - Drug Ther Bull SP - 91 LP - 96 DO - 10.1136/dtb.2003.411291 VL - 41 IS - 12 A2 - , Y1 - 2003/12/01 UR - http://dtb.bmj.com/content/41/12/91.abstract N2 - Around 1 in 1,000 adults in the UK has bronchiectasis, a potential outcome of various underlying lung diseases.1,2 It results from a 'vicious circle' of recurrent infection, inflammation, excessive mucus production, reduced mucociliary clearance, and dilatation and destruction of bronchi.1–4 Associated damage to blood vessels can lead to haemoptysis, which is usually slight, but may be severe.1 Bronchiectasis may be limited to one area (localised) or be more widespread (generalised). It can reduce lung function and quality of life, and may lead to respiratory failure and premature death.1 Here we review the management of patients with bronchiectasis. ER -