%0 Journal Article %T Controlled-release budesonide in Crohn's disease %D 1997 %R 10.1136/dtb.1997.35430 %J Drug and Therapeutics Bulletin %P 30-31 %V 35 %N 4 %X Relevant BNF section: 1.5Budesonide is a glucocorticoid with high local activity but much lower systemic availability than prednisolone. Topical formulations have long been licensed for use in asthma and rhinitis. Here we discuss a new orally active controlled-release preparation of budesonide (Entocort CR - Astra) formulated specifically for treating patients with Crohn's disease affecting the ileum and/or ascending colon. The manufacturer claims that the preparation "targets the ileum and ileocaecal area, achieving rapid results equivalent to prednisolone" with a "low level of systemic steroid side effects". %U https://dtb.bmj.com/content/dtb/35/4/30.full.pdf