TY - JOUR T1 - Managing subclinical hypothyroidism JF - Drug and Therapeutics Bulletin JO - Drug Ther Bull SP - 1 LP - 3 DO - 10.1136/dtb.1998.3611 VL - 36 IS - 1 A2 - , Y1 - 1998/01/01 UR - http://dtb.bmj.com/content/36/1/1.abstract N2 - Relevant BNF section: 6.2.1In a patient with overt primary hypothyroidism, management is usually straightforward: treatment with thyroxine should be offered to anyone with characteristic clinical features, a raised serum thyroid stimulating hormone (TSH) concentration and a low serum thyroxine (T4) concentration. More difficult is the management of a patient with subclinical hypothyroidism, in whom serum TSH is raised but T4 level is normal, and who is either asymptomatic or has only non-specific symptoms. Left untreated, some of these patients will eventually develop overt hypothyroidism. Here we discuss the use of thyroxine in patients with subclinical hypothyroidism. ER -