PT  - JOURNAL ARTICLE
ED  - ,
TI  - Parenteral corticosteroids in emergency
AID  - 10.1136/dtb.5.2.6
DP  - 1967 Jan 20
TA  - Drug and Therapeutics Bulletin
PG  - 6--7
VI  - 5
IP  - 2
4099  - http://dtb.bmj.com/content/5/2/6.short
4100  - http://dtb.bmj.com/content/5/2/6.full
SO  - Drug Ther Bull1967 Jan 20; 5
AB  - Corticosteroids are well absorbed from the gut: plasma concentrations of prednisolone or hydrocortisone are at a maximum about 2 hours after a single oral dose.1 An intramuscular dose acts no more quickly. Intravenous corticosteroid acts at once and is required for severe acute adrenal failure, for example in the crises of Addison’s disease, after adrenalectomy, after sudden cessation of corticosteroid therapy and sometimes in severe hypopituitarism. A sudden increase in the requirement of patients who are taking or have taken corticosteroids may also demand intravenous therapy.