PT - JOURNAL ARTICLE ED - , TI - Managing empyema in adults AID - 10.1136/dtb.2006.44317 DP - 2006 Mar 01 TA - Drug and Therapeutics Bulletin PG - 17--21 VI - 44 IP - 3 4099 - http://dtb.bmj.com/content/44/3/17.short 4100 - http://dtb.bmj.com/content/44/3/17.full SO - Drug Ther Bull2006 Mar 01; 44 AB - A collection of pus in the pleural space (empyema) is a dangerous condition that is usually a complication of pneumonia. Empyema can be associated with a delayed response of pneumonia to antibacterial treatment.1 It can lead to septicaemia, disseminated abscesses and prolonged hospitalisation.1–3 Reported mortality rates are typically 7-33%,2–6 but may exceed 50% in elderly patients or those with significant comorbidity, such as malignancy, diabetes mellitus or alcohol abuse.3,5,7 Here we review the management of adults with empyema.