RT Journal Article
SR Electronic
T1 A glossary of molecular genetics
JF Drug and Therapeutics Bulletin
JO Drug Ther Bull
FD BMJ Publishing Group Ltd
SP 15
OP 16
DO 10.1136/dtb.1996.34215
VO 34
IS 2
YR 1996
UL http://dtb.bmj.com/content/34/2/15.abstract
AB Techniques are now available for isolating genes, for determining their structure and function at the molecular level and for using them in various ways to diagnose and treat disease. Many, possibly most(!), non-specialists may not be familiar with the terminology of molecular genetics. Here we offer a glossary of terms that are now encountered in general medical journals, in clinical practice and in material published by the pharmaceutical industry. We begin, however, with a brief description of the basic mechanisms of inheritance and protein synthesis and examples of clinical applications of gene manipulation.