RT Journal Article SR Electronic T1 Exceptionally difficult JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 121 OP 121 DO 10.1136/dtb.2011.02.0064 VO 49 IS 11 YR 2011 UL http://dtb.bmj.com/content/49/11/121.abstract AB