PT  - JOURNAL ARTICLE
ED  - ,
TI  - Reducing NSAID-induced gastrointestinal complications
AID  - 10.1136/dtb.2011.02.0007
DP  - 2011 Feb 01
TA  - Drug and Therapeutics Bulletin
PG  - 18--21
VI  - 49
IP  - 2
4099  - http://dtb.bmj.com/content/49/2/18.short
4100  - http://dtb.bmj.com/content/49/2/18.full
SO  - Drug Ther Bull2011 Feb 01; 49
AB  - Relevant BNF section: BNF 10.1.1 Around 17 million items for non-steroidal anti-inflammatory drugs (NSAIDs) are prescribed annually in England alone.1 These drugs are associated with upper gastrointestinal complications.2 For example, each year, NSAIDs cause about 3,500 hospitalisations for, and 400 deaths from, ulcer bleeding in people aged 60 years or above.3 Aspirin, even in low doses, is also associated with gastrointestinal complications.4 5 Here we assess strategies for reducing gastrointestinal complications induced by NSAIDs, including aspirin and selective inhibitors of cyclo-oxygenase-2 (coxibs).