RT Journal Article SR Electronic T1 Frameless intra-uterine contraceptive device JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 21 OP 22 DO 10.1136/dtb.2002.40321 VO 40 IS 3 YR 2002 UL http://dtb.bmj.com/content/40/3/21.abstract AB Relevant BNF section: 7.3.4Modern copper-containing contraceptive intra-uterine devices (IUDs) typically comprise a solid plastic frame loaded with copper wire and/or copper sleeves. Although they are very effective (annual pregnancy rates generally below 1%), some women discontinue their use within a year after insertion because of excessive bleeding and/or painful periods (4-15%), or because the device has been spontaneously expelled (2-8%).1 GyneFix (Contrel) is a new IUD approved for up to 5 years of use. Its manufacturer claims that the device produces fewer unwanted effects, and is less likely to be expelled, than conventional IUDs because it does not have a plastic frame (a frameless device). Here we assess these claims.