PT - JOURNAL ARTICLE ED - , TI - Chemotherapy for metastatic colorectal cancer AID - 10.1136/dtb.2002.40749 DP - 2002 Jul 01 TA - Drug and Therapeutics Bulletin PG - 49--52 VI - 40 IP - 7 4099 - http://dtb.bmj.com/content/40/7/49.short 4100 - http://dtb.bmj.com/content/40/7/49.full SO - Drug Ther Bull2002 Jul 01; 40 AB - Relevant BNF section: 8.1Of the 30,000 people in the UK who develop colorectal cancer each year, around 70-80% undergo potentially curative surgery. Even so, around a half of all patients eventually die from metastatic disease,1 typically within 5 years of diagnosis. Many patients who develop metastases are offered systemic chemotherapy to try to extend survival and maintain or improve quality of life. How effective is such intervention?