RT Journal Article SR Electronic T1 Chemotherapy for metastatic colorectal cancer JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 49 OP 52 DO 10.1136/dtb.2002.40749 VO 40 IS 7 YR 2002 UL http://dtb.bmj.com/content/40/7/49.abstract AB Relevant BNF section: 8.1Of the 30,000 people in the UK who develop colorectal cancer each year, around 70-80% undergo potentially curative surgery. Even so, around a half of all patients eventually die from metastatic disease,1 typically within 5 years of diagnosis. Many patients who develop metastases are offered systemic chemotherapy to try to extend survival and maintain or improve quality of life. How effective is such intervention?