RT Journal Article
SR Electronic
T1 Chemotherapy in malignant disease
JF Drug and Therapeutics Bulletin
JO Drug Ther Bull
FD BMJ Publishing Group Ltd
SP 13
OP 16
DO 10.1136/dtb.8.4.13
VO 8
IS 4
YR 1970
UL http://dtb.bmj.com/content/8/4/13.abstract
AB Cancer chemotherapy, unlike antimicrobial chemotherapy, is not based on absolute metabolic differences between cancer cells and normal human cells. Anticancer agents inhibit the growth of cells, whether normal or malignant, though different types of cell vary in their susceptibility to these agents, and in their capacity for recovery. The usefulness of these drugs is thus limited by their effects on normal cells.