RT Journal Article SR Electronic T1 Biguanides reassessed JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 7 OP 8 DO 10.1136/dtb.7.2.7 VO 7 IS 2 YR 1969 UL http://dtb.bmj.com/content/7/2/7.abstract AB The biguanides phenformin (Dibotin - Bayer) and metformin (Glucophage - Rona) have been used in the treatment of diabetes for about 10 years. Continuing experience and many new observations have gradually led to changes in their clinical use.