PT - JOURNAL ARTICLE ED - , TI - ▼ Sacubitril valsartan for heart failure AID - 10.1136/dtb.2016.6.0405 DP - 2016 Jun 01 TA - Drug and Therapeutics Bulletin PG - 66--69 VI - 54 IP - 6 4099 - http://dtb.bmj.com/content/54/6/66.short 4100 - http://dtb.bmj.com/content/54/6/66.full SO - Drug Ther Bull2016 Jun 01; 54 AB - ▼ Sacubitril valsartan (Entresto—Novartis) is a new oral drug licensed for the treatment of symptomatic chronic heart failure in adults with reduced ejection fraction.1 It is described as an angiotensin receptor neprilysin inhibitor and contains the neprilysin inhibitor, sacubitril and the angiotensin II receptor antagonist, valsartan.1-3 Here, we review the evidence for sacubitril valsartan and consider its place in the management of heart failure.