RT Journal Article SR Electronic T1 ▼ Sacubitril valsartan for heart failure JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 66 OP 69 DO 10.1136/dtb.2016.6.0405 VO 54 IS 6 YR 2016 UL http://dtb.bmj.com/content/54/6/66.abstract AB ▼ Sacubitril valsartan (Entresto—Novartis) is a new oral drug licensed for the treatment of symptomatic chronic heart failure in adults with reduced ejection fraction.1 It is described as an angiotensin receptor neprilysin inhibitor and contains the neprilysin inhibitor, sacubitril and the angiotensin II receptor antagonist, valsartan.1-3 Here, we review the evidence for sacubitril valsartan and consider its place in the management of heart failure.