TY - JOUR T1 - The problem with unregulated botanicals JF - Drug and Therapeutics Bulletin JO - Drug Ther Bull SP - 61 LP - 61 DO - 10.1136/dtb.2016.6.0403 VL - 54 IS - 6 A2 - , Y1 - 2016/06/01 UR - http://dtb.bmj.com/content/54/6/61.abstract N2 - In 2011, after a transition period of 7 years, the traditional herbal registration (THR) scheme implemented by the Medicines and Healthcare products Regulatory Agency (MHRA) came into full force.1 The scheme permits the registration of plant-based products that are used for minor self-limiting conditions where medical supervision is not required, based on evidence of long-standing use rather than proven clinical efficacy. Applicants have to follow rigorous quality assurance procedures, meet requirements for demonstrating safety and pharmacovigilance and establish sustainable and well-defined value chains (the sequence of activities required to … ER -