TY - JOUR T1 - Comparison of antibiotics for <em>Clostridium difficile</em> infection JF - Drug and Therapeutics Bulletin JO - Drug Ther Bull SP - 71 LP - 72 DO - 10.1136/dtb.2019.000022 VL - 57 IS - 5 A2 - , Y1 - 2019/05/01 UR - http://dtb.bmj.com/content/57/5/71.abstract N2 - Review of: Beinortas T, et al. Comparative efficacy of treatments for Clostridium difficile infection: a systematic review and network meta-analysis. Lancet Infect Dis 2018;18:1035–44.Key learning pointsA comparison of 13 drug treatments for Clostridium difficile found high-quality evidence that fidaxomicin was the most effective treatment in providing a long-term cure.Fidaxomicin was a better option than vancomycin for all patients except those with severe infections.Metronidazole was ranked as 11th of 13 drugs in terms of efficacy.The authors of a network meta-analysis of drugs to treat Clostridium difficile infection have suggested that for non-multiply recurrent infections, fidaxomicin is a better option than vancomycin in all but the most severe infections, and that oral metronidazole … ER -