Ninety patients with lymph node tuberculosis were treated with either rifampicin and isoniazid or ethambutol and isoniazid for 18 months, supplemented by sheptomycin for the first two months. No differences emerged between the two regimens, either during treatment or during an 18 month post-chemotherapy follow-up. In 7% of patients lymph nodes enlarged transiently after the end of treatment and in 7% enlarged nodes persisted. No patient required further treatment. One patient was left with an intermittently discharging sinus in an operation scar.