A Swedish cohort study has investigated a possible link between oral fluoroquinolones and an increased risk of aortic aneurysm or dissection.1 Fluoroquinolone use is known to increase the risk of tendon disorders, including Achilles tendon rupture and tendinopathy, through degradation of collagen and other structural tissues. Previous observational studies have raised concerns that fluoroquinolones could increase the risk of aortic aneurysm or dissection, prompting the European Medicines Agency (EMA) to initiate further assessment.2,3

The study used linked registry data on patient characteristics, filled prescriptions and cases of …