Abstract

Glutaraldehyde cross-linked (GAX) collagen (Contigen Bard Collagen Implant-Bard Ltd), a bovine product, was introduced last year for the treatment of "urinary incontinence due to intrinsic sphincter deficiency (poor or non-functioning bladder outlet mechanism)". The manufacturer claims that injecting GAX collagen into tissues around the bladder neck and urethra provides a "simple, safe, efficacious alternative to surgery". We assess these claims.