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What is the faecal calprotectin test?

Abstract

Calprotectin is a protein released by white blood cells involved in inflammation of the bowel.1 It can be detected in faeces using laboratory or point of care tests. Although an elevated calprotectin level indicates inflammation in the bowel, it cannot identify the cause.1 Faecal calprotectin testing is mainly used in distinguishing between ‘functional’ disorders such as irritable bowel syndrome and ‘organic’ disorders, such as inflammatory bowel disease, a group of conditions including Crohn's disease and ulcerative colitis that require referral to specialist services. Here we explain the role of faecal calprotectin testing in adults in primary care.

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