Article Text

Download PDFPDF

A new local anaesthetic


Bupivacaine (Marcain - DFE), which is advocated as a long-acting local anaesthetic, was synthesised in Sweden in 1957. Chemically bupivacaine and its predecessor mepivacaine (which is not available in this country) are related to lignocaine. Bupivacaine differs from mepivacaine in having a butyl instead of a methyl group attached to the piperidyl ring.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.