You are here

Article Text

Article menu
Download PDFPDF
DTB Select
Which drugs are best for treating severe hypertension in pregnancy?

https://doi.org/10.1136/dtb.2019.000014

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Review of: Sridharan K and Sequeira RP. Drugs for treating severe hypertension in pregnancy: a network analysis and trial sequential analysis of randomized clinical trials. Br J Clin Pharmacol 2018; 84:1906–16.

    Key learning points

    • There is a lack of head-to-head trials of drugs to treat severe hypertension in pregnancy.

    • This is the first network meta-analysis of anti-hypertensive treatments for this indication.

    • The authors concluded that labetalol, hydralazine and nifedipine have similar efficacy.

    • There were no major differences in safety between treatments.

    Summary

    A network meta-analysis of drugs to treat severe hypertension in pregnancy found moderate quality evidence of similar efficacy between nifedipine, hydralazine and labetalol with subtle differences in safety.1

    Overview

    This network analysis of randomised controlled trials compared drugs for severe hypertension in pregnancy.1 The primary outcome was the number of patients achieving target blood pressure (BP). The …

    View Full Text

    Footnotes

    • Provenance and peer review Commissioned; internally peer reviewed.

    • Contributors DTB Team.