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The diagnosis and management of pre-eclampsia have long challenged healthcare professionals and pregnant women alike. Pre-eclampsia affects at least 3% of women in their first pregnancy, is a leading cause of maternal and fetal morbidity and mortality and may account for 20% of UK antenatal admissions. Options for preventing pre-eclampsia are limited and are largely based on the use of low-dose aspirin from the beginning of the second trimester.1 Management options have not changed substantially since the introduction of magnesium sulfate for treatment and prevention of eclamptic seizures. While pharmacological control of blood pressure reduces the likelihood of stroke, ‘curing’ pre-eclampsia is still possible only through delivery. For pre-eclampsia at term, this is accepted as best practice. For preterm pre-eclampsia, the best timing …
Competing interests None declared. Disclosure of conflicts of interest form(s) are published online as supplementary files.
Provenance and peer review Commissioned; externally peer reviewed.